XXI – The World? – Spawns a trap door to a crawl space. Unlock method – Defeat Ultra Greedier as Tainted Lazarus XXI – The World? XX – Judgement? – Spawns a Restock Machine. Unlock method – Defeat Ultra Greedier as Tainted Jacob XX – Judgement? Also causes Curse of Darkness that cannot be dispelled. Turns Isaac’s red hearts into bone hearts, but they revert once the effect ends. XIX – The Sun? – Gain Spirit of the Night and +1.5 damage for the current level. Unlock method – Defeat Ultra Greedier as Tainted Jacob XIX – The Sun? The pathway back to the normal rooms will be made of red rooms. XVIII – The Moon? – Teleports the player to the Ultra Secret Room. Unlock method – Ultra Greedier as Tainted Isaac XVIII – The Moon? XVII – The Stars? – Removes Isaac’s oldest passive item and spawns 2 random items from the current room’s item pool. Unlock method – Defeat Ultra Greedier as Tainted Apollyon XVII – The Stars? The pathways between exits can’t be blocked. XVI – The Tower? – Spawns 6 clusters of random rocks and other obstacles.

Unlock method – Defeat Ultra Greedier as Tainted Azazel XVI – The Tower? XV – The Devil? – Invokes The Bible and grants Seraphim familiar and flight for 30 seconds. Unlock method – Ultra Greedier as Tainted Samson XI – Strength? – All enemies in the room are weakened, becoming slow and take double damage. Unlock method – Ultra Greedier as Tainted Cain XI – Strength? X – Wheel of Fortune? – Invokes a random dice room effect. Unlock method – Complete Red Redemption (challenge #44) X – Wheel of Fortune? If there is nothing to sell, spawns a penny. IX – The Hermit? – “Sells” items and pickups in the room for their usual shop price, spawning a matching amount of coins. Unlock method – Complete Cantripped (challenge #43) IX – The Hermit? VIII – Justice? – Spawns 2 to 4 Golden Chests. Unlock method – Complete Hot Potato (challenge #42) VIII – Justice? Edith is the secret character from mod Antibirth.

VII – The Chariot? – Isaac becomes an invincible, immobile statue with extreme fire rate for 10 seconds. Unlock method – Defeat Ultra Greedier as Tainted Magdalene VII – The Chariot? Turns 1 red heart container or 2 soul hearts into a broken heart, potentially fatally. VI – The Lovers? – Spawns a random item from the current room’s item pool.

Binding of isaac the stars